Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 1
1994 1
1995 1
1996 1
1997 3
1998 3
1999 2
2000 5
2001 3
2002 6
2003 4
2004 9
2005 4
2006 4
2007 6
2008 7
2009 6
2010 4
2011 6
2012 8
2013 8
2014 5
2015 7
2016 8
2017 8
2018 6
2019 8
2020 7
2021 3
2022 4
2023 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

134 results

Results by year

Filters applied: . Clear all
Page 1
Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment.
Zhang M, Hu W, Cai C, Wu Y, Li J, Dong S. Zhang M, et al. Mater Today Bio. 2022 Feb 21;14:100223. doi: 10.1016/j.mtbio.2022.100223. eCollection 2022 Mar. Mater Today Bio. 2022. PMID: 35243298 Free PMC article. Review.
The review also explores the progress and challenges with the use of stimuli-responsive nanomaterials to manage inflammatory arthritis based on pathological changes, including cartilage degeneration, synovitis, and subchondral bone destruction. Exposure to appropriate stim …
The review also explores the progress and challenges with the use of stimuli-responsive nanomaterials to manage inflammatory arthritis based …
The Critical Role of Growth Factors in Gastric Ulcer Healing: The Cellular and Molecular Mechanisms and Potential Clinical Implications.
Tarnawski AS, Ahluwalia A. Tarnawski AS, et al. Cells. 2021 Aug 2;10(8):1964. doi: 10.3390/cells10081964. Cells. 2021. PMID: 34440733 Free PMC article. Review.
These growth factors bind to their receptors and trigger cell proliferation, migration, and survival pathways through Ras, MAPK, PI3K/Akt, PLC-gamma, and Rho/Rac/actin signaling. The triggers for the activation of these growth factors are tissue injury and hypoxia. …
These growth factors bind to their receptors and trigger cell proliferation, migration, and survival pathways through Ras, MAPK, PI3K/Akt, …
G-CSF drives autoinflammation in APLAID.
Mulazzani E, Kong K, Aróstegui JI, Ng AP, Ranathunga N, Abeysekera W, Garnham AL, Ng SL, Baker PJ, Jackson JT, Lich JD, Hibbs ML, Wicks IP, Louis C, Masters SL. Mulazzani E, et al. Nat Immunol. 2023 May;24(5):814-826. doi: 10.1038/s41590-023-01473-6. Epub 2023 Mar 30. Nat Immunol. 2023. PMID: 36997670 Free PMC article.
Missense mutations in PLCG2 can cause autoinflammation with phospholipase C gamma 2-associated antibody deficiency and immune dysregulation (APLAID). ...Furthermore, excessive myelopoiesis was normalized and lymphocyte numbers rebounded. APLAID mice were also …
Missense mutations in PLCG2 can cause autoinflammation with phospholipase C gamma 2-associated antibody deficiency and …
Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLCγ1-Ca2+-NFATc1 signaling pathway.
Zeng XZ, Zhang YY, Yang Q, Wang S, Zou BH, Tan YH, Zou M, Liu SW, Li XJ. Zeng XZ, et al. Acta Pharmacol Sin. 2020 Feb;41(2):229-236. doi: 10.1038/s41401-019-0289-6. Epub 2019 Aug 20. Acta Pharmacol Sin. 2020. PMID: 31431733 Free PMC article.
In chronic infectious diseases caused by gram-negative bacteria, such as osteomyelitis, septic arthritis, and periodontitis, osteoclastic activity is enhanced with elevated inflammation, which disturbs the bone homeostasis and results in osteolysis. Lipopolysaccharide (LPS …
In chronic infectious diseases caused by gram-negative bacteria, such as osteomyelitis, septic arthritis, and periodontitis, osteoclastic ac …
Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.
Mazharian A, Thomas SG, Dhanjal TS, Buckley CD, Watson SP. Mazharian A, et al. Blood. 2010 Aug 5;116(5):793-800. doi: 10.1182/blood-2010-03-275990. Epub 2010 May 10. Blood. 2010. PMID: 20457868 Free article.
In this study, we explore the role of surface glycoprotein receptors and signaling proteins in regulating MK migration and platelet recovery after immune-induced thrombocytopenia. We show that spreading and migration of mouse primary bone marrow-derived MKs on a fibronecti …
In this study, we explore the role of surface glycoprotein receptors and signaling proteins in regulating MK migration and platelet recovery …
Tenascin-C: Form versus function.
Giblin SP, Midwood KS. Giblin SP, et al. Cell Adh Migr. 2015;9(1-2):48-82. doi: 10.4161/19336918.2014.987587. Cell Adh Migr. 2015. PMID: 25482829 Free PMC article. Review.
Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways.
Gluschko A, Farid A, Herb M, Grumme D, Krönke M, Schramm M. Gluschko A, et al. Autophagy. 2022 May;18(5):1090-1107. doi: 10.1080/15548627.2021.1969765. Epub 2021 Sep 5. Autophagy. 2022. PMID: 34482812 Free PMC article.
Non-canonical autophagy pathways decorate single-membrane vesicles with Atg8-family proteins such as MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3). Phagosomes containing the bacterial pathogen Listeria monocytogenes (L.m.) can be targeted by a non-canonical …
Non-canonical autophagy pathways decorate single-membrane vesicles with Atg8-family proteins such as MAP1LC3/LC3 (microtubule-associated pro …
ASP2-1, a polysaccharide from Acorus tatarinowii Schott, inhibits osteoclastogenesis via modulation of NFATc1 and attenuates LPS-induced bone loss in mice.
Wang J, Zhang Y, Xu X, Jin W, Jing C, Leng X, Wang M, Cao J, Wang HB, Sun L. Wang J, et al. Int J Biol Macromol. 2020 Dec 15;165(Pt B):2219-2230. doi: 10.1016/j.ijbiomac.2020.10.077. Epub 2020 Oct 22. Int J Biol Macromol. 2020. PMID: 33132123
Staining (H&E, TRAP) and micro-CT assays revealed ASP2-1 attenuated bone destruction and osteoclast over-activation and improved tibia micro-architecture in a murine LPS-induced bone loss model. Thus, ASP2-1 may alleviate inflammatory bone l …
Staining (H&E, TRAP) and micro-CT assays revealed ASP2-1 attenuated bone destruction and osteoclast over-activation and im …
GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone mass.
Menon P, Yin G, Smolock EM, Zuscik MJ, Yan C, Berk BC. Menon P, et al. J Cell Physiol. 2010 Nov;225(3):777-85. doi: 10.1002/jcp.22282. J Cell Physiol. 2010. PMID: 20568227 Free PMC article.
Because GIT1 is tyrosine phosphorylated by Src kinase, we anticipated that GIT1 KO should have a bone phenotype similar to Src KO. Microcomputed tomography of the long bones revealed that GIT1 KO mice have a 2.3-fold increase in bone mass compared to wild-typ …
Because GIT1 is tyrosine phosphorylated by Src kinase, we anticipated that GIT1 KO should have a bone phenotype similar to Src KO. Mi …
Association of protein-tyrosine kinase with phospholipase C-gamma 1 in bone marrow-derived mouse mast cells.
Fukamachi H, Kawakami Y, Takei M, Ishizaka T, Ishizaka K, Kawakami T. Fukamachi H, et al. Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9524-8. doi: 10.1073/pnas.89.20.9524. Proc Natl Acad Sci U S A. 1992. PMID: 1384056 Free PMC article.
Bone marrow-derived mouse mast cells contain phospholipase C-gamma 1 (PLC-gamma 1), which is phosphorylated at tyrosine residues upon cross-linking of cell-bound IgE antibodies with multivalent antigen. ...Neither beta nor …
Bone marrow-derived mouse mast cells contain phospholipase C-gamma 1 (PLC-gamma 1), …
134 results